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1.
PLoS One ; 16(11): e0258810, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34739487

RESUMO

This analytical cross-sectional study aimed to assess the correlation of oral health literacy (OHL) and oral health status and behavior in participants of a pre-marriage counseling program. Also, it aimed to determine the target population's OHL needs to design necessary interventions. A total of 828 couples with a mean age of 24.22 years participating in a pre-marriage counseling program were evaluated. Data were collected using the oral health literacy-adult questionnaire (OHL-AQ). Clinical oral examinations were performed to measure the gingival index (GI), plaque index (PI), and DMFT. The mean OHL score of the couples was 7.86±3.83 out of 17; while, the mean DMFT score was 6.30±5.73. After controlling for the confounders, OHL had a significant correlation with the frequency of dental visits, and smoking status, and inverse correlation with the number of decayed teeth and missing teeth, and PI, and GI (p<0.05). The current results highlight the necessity of OHL interventions to fill the existing gaps. This is an unmet need of the couples, and such interventions are required to promote their own oral health as well as the oral health of their future children.


Assuntos
Escala de Avaliação Comportamental/estatística & dados numéricos , Saúde Bucal/estatística & dados numéricos , Adolescente , Adulto , Aconselhamento , Estudos Transversais , Assistência Odontológica , Feminino , Letramento em Saúde , Humanos , Masculino , Casamento , Índice Periodontal , Inquéritos e Questionários
3.
J Int Neuropsychol Soc ; 26(10): 1036-1044, 2020 11.
Artigo em Inglês | MEDLINE | ID: mdl-32641198

RESUMO

OBJECTIVE: Executive function (EF) difficulties are commonly found in youth with intellectual disability (ID). Given mixed results from studies using performance-based EF measures, the EF profile has not been well characterized for this population. No published work has examined the clinical utility of the Behavior Rating Inventory of Executive Function, Second Edition (BRIEF2) in distinguishing EF in ID. We hypothesized that the BRIEF2 would show greater elevations in youth with ID compared to the Average IQ comparison group. METHODS: Participants included a large sample of 504 youth (157 in ID group; aged 8-18 years) referred for (neuro)psychological evaluation (2015-2019) and identified as meeting criteria for either ID or Average IQ comparison group. RESULTS: Significant elevations were found across BRIEF2 indices and scales. Only mild elevations were noted in selective cognitive regulation scales within the Average IQ group. Groups differed significantly across all EF dimensions, with greater differences observed in behavioral regulation (Self-Monitoring, Inhibition), Shift, and Working Memory. An elevated but less variable pattern of index scores was noted in ID, while the overall pattern of scaled scores appeared similar between groups. CONCLUSIONS: The less variable and consistently elevated profile may suggest fewer EF dimensions in individuals with ID than the model proposed in the test manual. Similar profiles between groups may reflect differences in severity, rather than differences in constructs measured by the EF factors, per se. Additional examination is needed to confirm potential structural differences in EF for youth with ID as measured by BRIEF2, with a clinical implication for greater efficiency of EF assessment in this population.


Assuntos
Escala de Avaliação Comportamental/estatística & dados numéricos , Função Executiva , Deficiência Intelectual/psicologia , Adolescente , Criança , Feminino , Humanos , Inibição Psicológica , Masculino , Memória de Curto Prazo , Testes Neuropsicológicos , Adulto Jovem
4.
Acta Neuropsychiatr ; 32(6): 293-302, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-32378506

RESUMO

Objective and rationale: Animal models are critical for the study of mental disorders and their treatments but are repeatedly criticized for problems with validity and reproducibility. One approach to enhance validity and reproducibility of models is to use test batteries rather than single tests. Yet, a question regarding batteries is whether one can expect a consistent individual behavioural phenotype in mice across tests that can be presumed to be part of the same construct. This study was designed to explore the relationship between the behaviours of mice across tests in some variations of test batteries for depression- and anxiety-like behaviours. Methods: Female and male healthy, intact, and untreated mice from the ICR and black Swiss strains were used in four separate experiments. With some variations, mice were exposed to a battery of behavioural tests representing affective- and anxiety-like behaviours. Data were analysed for differences between sexes and for correlations between behaviours within and across the tests in the battery. Results: No differences were found between the sexes. With very few exceptions, we found correlations within tests (when one test has more than one measure or is repeated) but not across different tests within the battery. Conclusions: The results cast some doubt on the utility of behavioural test batteries to represent different facets of emotional behaviour in healthy intact outbred mice, without any interventions or treatments. Additional studies are designed to explore whether stronger relationship between the tests will appear after manipulations or drug treatments.


Assuntos
Ansiedade/diagnóstico , Escala de Avaliação Comportamental/estatística & dados numéricos , Comportamento Animal/fisiologia , Depressão/diagnóstico , Animais , Ansiedade/psicologia , Depressão/psicologia , Modelos Animais de Doenças , Emoções/fisiologia , Feminino , Masculino , Aprendizagem em Labirinto/fisiologia , Camundongos , Camundongos Endogâmicos ICR , Reprodutibilidade dos Testes
5.
J Pharmacokinet Pharmacodyn ; 47(3): 241-253, 2020 06.
Artigo em Inglês | MEDLINE | ID: mdl-32285302

RESUMO

This manuscript aims to present the first item response theory (IRT) model within a pharmacometric framework to characterize the longitudinal changes of Aberrant Behavior Checklist (ABC) data in children with autism. Data were obtained from 120 patients, which included 20,880 observations of the 58 items for up to three months. Observed scores for each ABC item were modeled as a function of the subject's disability. Longitudinal IRT models with five latent disability variables based on ABC subscales were used to describe the irritability, lethargy, stereotypic behavior, hyperactivity, and inappropriate speech over time. The IRT pharmacometric models could accurately describe the longitudinal changes of the patient's disability while estimating different time-course of disability for the subscales. For all subscales, model-estimated disability was reduced following initiation of therapy, most markedly for hyperactivity. The developed framework provides a description of ABC longitudinal data that can be a suitable alternative to traditional ABC data collected in autism clinical trials. IRT is a powerful tool with the ability to capture the heterogeneous nature of ABC, which results in more accurate analysis in comparison to traditional approaches.


Assuntos
Antipsicóticos/farmacologia , Transtorno Autístico/tratamento farmacológico , Escala de Avaliação Comportamental/estatística & dados numéricos , Comportamento Infantil/efeitos dos fármacos , Avaliação da Deficiência , Antipsicóticos/uso terapêutico , Transtorno Autístico/diagnóstico , Lista de Checagem/estatística & dados numéricos , Criança , Pré-Escolar , Feminino , Humanos , Estudos Longitudinais , Masculino , Resultado do Tratamento
6.
J Biosci ; 452020.
Artigo em Inglês | MEDLINE | ID: mdl-32020904

RESUMO

In primates, males compete for a mate, which is a non-sharable resource. This makes the conditions less conducive for males to have stable relationships. One such special kind of relationship is a bond where the interactions are reciprocated, equitable and differentiated. Bonds in macaque societies are based on the degree of within-group contest competition for mates which is dependent on the synchronization of female fertile phase and reliability of fertility signals. Species of the Fascicularis group, including Nicobar subspecies, show intermediate reliability in the signals with mild peaks, and studies have shown reciprocity but no differentiation. We conducted a study on a group of wild Nicobar long-tailed macaques Macaca fascicularis umbrosus to understand the existing patterns of male-male relationships. We examined whether there is reciprocity in affiliation among the individuals and whether the rate of affiliation is balanced. We also measured the dominance linearity and steepness in the group to understand the monopolizability of females. We used social network analysis to understand whether the relations are differentiated based on hierarchical position and whether the high-ranking individuals are the most central individuals in the distribution of grooming in the group. We found that there is reciprocity among the males although that is not equitable. There was no rankrelated differentiation of affiliation among the males of the group. Instead, the identities of individuals influenced affiliation patterns. Our results correspond to the existent strong relationships but lack of social bond otherwise found in the Fascicularis group of macaques.


Assuntos
Técnicas de Observação do Comportamento/estatística & dados numéricos , Escala de Avaliação Comportamental/estatística & dados numéricos , Comportamento Animal , Macaca fascicularis/psicologia , Comportamento Social , Animais , Asseio Animal , Masculino , Predomínio Social
7.
Am J Drug Alcohol Abuse ; 46(2): 158-166, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31490713

RESUMO

Background: Stigma toward substance users is a barrier to seeking treatment.Objective: The aim for this paper was to examine the psychometric properties of the Perceived Stigma Toward Substance Users (PSAS) and its relationship with help-seeking variables.Methods: College students (N = 791; nfemales = 557, 70%) responded to the PSAS and other help-seeking-related measures in an online study.Results: Confirmatory factor analysis supported a unidimensional factor structure and acceptable model fit after modifications (CFI = .961; TLI = .937; RMSEA = .067, 90% C.I. = .050 to .085; SRMR = .035). Results indicated good internal consistency estimates (α = .80; ω = .80). The PSAS was negatively associated with intent to seek treatment for substance issues and willingness to self-disclose negative emotions. The PSAS was also positively correlated with stigma associated with seeking help for mental health issues, attitudes concerning risk associated with help-seeking, self-concealment, anticipated risks associated with seeking treatment. When embedded within a larger path model that predicts intent to seek treatment for substance use issues (CFI = .925; TLI = .895; RMSEA = .061, 90%C.I. = .052 to .069; pclose fit = .019; SRMR = .049), the PSAS had an incremental contribution to predicting the criterion variable even after accounting for frequency of alcohol use-related problems, and stigma and attitudes associated with seeking help for general mental health issues.Conclusion: These findings provide further reliability and validity evidence for PSAS, especially in relation to help-seeking variables. Reducing stigma toward substance users can help increase treatment utilization.


Assuntos
Escala de Avaliação Comportamental/estatística & dados numéricos , Usuários de Drogas/psicologia , Aceitação pelo Paciente de Cuidados de Saúde/psicologia , Estigma Social , Transtornos Relacionados ao Uso de Substâncias/psicologia , Feminino , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Masculino , Psicometria , Inquéritos e Questionários/estatística & dados numéricos , Adulto Jovem
8.
J Intensive Care Med ; 35(5): 453-460, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-29448873

RESUMO

BACKGROUND: Self-reported and behavioral pain assessment scales are often used interchangeably in critically ill patients due to fluctuations in mental status. The correlation between scales is not well elucidated. The purpose of this study was to describe the correlation between self-reported and behavioral pain scores in critically ill patients. METHODS: Pain was assessed using behavioral and self-reported pain assessment tools. Behavioral pain tools included Critical Care Pain Observation Tool (CPOT) and Behavioral Pain Scale (BPS). Self-reported pain tools included Numeric Rating Scale (NRS) and Wong-Baker Faces Pain Scales. Delirium was assessed using the confusion assessment method for the intensive care unit. Patient preference regarding pain assessment method was queried. Correlation between scores was evaluated. RESULTS: A total of 115 patients were included: 67 patients were nondelirious and 48 patients were delirious. The overall correlation between self-reported (NRS) and behavioral (CPOT) pain scales was poor (0.30, P = .018). In patients without delirium, a strong correlation was found between the 2 behavioral pain scales (0.94, P < .0001) and 2 self-reported pain scales (0.77, P < .0001). Self-reported pain scale (NRS) and behavioral pain scale (CPOT) were poorly correlated with each other (0.28, P = .021). In patients with delirium, there was a strong correlation between behavioral pain scales (0.86, P < .0001) and a moderate correlation between self-reported pain scales (0.69, P < .0001). There was no apparent correlation between self-reported (NRS) and behavioral pain scales (CPOT) in patients with delirium (0.23, P = .12). Most participants preferred self-reported pain assessment. CONCLUSION: Self-reported pain scales and behavioral pain scales cannot be used interchangeably. Current validated behavioral pain scales may not accurately reflect self-reported pain in critically ill patients.


Assuntos
Escala de Avaliação Comportamental/estatística & dados numéricos , Cuidados Críticos/métodos , Estado Terminal/psicologia , Medição da Dor/métodos , Autorrelato/estatística & dados numéricos , Adulto , Idoso , Delírio/psicologia , Feminino , Humanos , Unidades de Terapia Intensiva , Masculino , Pessoa de Meia-Idade , Escores de Disfunção Orgânica , Medição da Dor/psicologia , Estudos Prospectivos , Reprodutibilidade dos Testes
9.
Int J Nurs Educ Scholarsh ; 16(1)2019 Dec 25.
Artigo em Inglês | MEDLINE | ID: mdl-31875489

RESUMO

Background Incivility in nursing education can negatively affect the academic achievement. As there is no tool in Arabic to assess incivility among nursing students, there is a need for a valid and reliable tool. Purpose This study aimed to investigate the psychometric properties of the Arabic version of the Incivility in Nursing Education- Revised (INE-R) survey. Method This cross-sectional study was conducted in four universities in Iraq using a convenience sampling strategy. A translated Arabic version of the INE-R was used to assess its validity and reliability. Results Three hundred eighty-nine surveys were included in the analysis. The contrast validity was confirmed by using Exploratory Factor Analysis. The internal consistency was tested using Cronbach's alpha, which showed the result of 0.87. Conclusion The Arabic version of the Incivility in Nursing Education- Revised is a valid and reliable scale. This scale can be used in Arab countries to assess incivility in nursing education.


Assuntos
Escala de Avaliação Comportamental/estatística & dados numéricos , Educação em Enfermagem , Incivilidade , Idioma , Psicometria/estatística & dados numéricos , Adulto , Estudos Transversais , Docentes de Enfermagem , Humanos , Relações Interprofissionais , Iraque , Masculino , Reprodutibilidade dos Testes , Meio Social , Estudantes de Enfermagem/psicologia , Adulto Jovem
10.
J Clin Psychiatry ; 80(6)2019 11 19.
Artigo em Inglês | MEDLINE | ID: mdl-31747488

RESUMO

OBJECTIVE: To compare the predictive accuracy of the Suicide Intent Scale (SIS), the Suicide Assessment Scale (SUAS), the Karolinska Interpersonal Violence Scale (KIVS), and the Columbia-Suicide Severity Rating Scale (C-SSRS) for suicide attempts and suicides within 3 and 12 months of an episode of self-harm. METHODS: This prospective multicenter cohort study included patients (N = 804) aged 18-95 years with a recent episode of self-harm assessed in psychiatric emergency settings from April 2012 to April 2016. Suicide attempts and suicides were identified in medical records and in the National Cause of Death Register. Receiver operating characteristic curves were constructed, and accuracy statistics were calculated. A sensitivity of at least 80% combined with a specificity of at least 50% were considered minimally acceptable. RESULTS: At least 1 suicide attempt was recorded for 216 participants during follow-up, and 19 participants died by suicide. The SUAS and C-SSRS were better than chance in classifying the 114 suicide attempts occurring within the first 3 months; a C-SSRS score ≥ 27 yielded a sensitivity/specificity of 79.8%/51.5% (P < .001). During 1-year follow-up, the SUAS and C-SSRS also performed better than chance, but no cutoff on either instrument gave a sensitivity/specificity of ≥ 80%/≥ 50%. The SIS was the only instrument that could classify suicides correctly. At 3 months, the area under the curve (AUC) was 0.94 (95% CI, 0.89-0.99), and a score ≥ 21 predicted suicide with a sensitivity/specificity of 100%/81.9%, based on only 4 suicides. At 1-year follow-up, the AUC was 0.74 (95% CI, 0.61-0.87), and a score ≥ 17 predicted suicide with a sensitivity/specificity of 72.2%/57.9%. CONCLUSIONS: Instruments that predicted nonfatal repeat suicide attempts did not predict suicide and vice versa. With the possible exception of the prediction of suicide by the SIS in a short time frame, the specificity of these instruments was low, giving them a limited relevance in the prediction of suicidal behaviors.


Assuntos
Escala de Avaliação Comportamental/estatística & dados numéricos , Medição de Risco/estatística & dados numéricos , Tentativa de Suicídio/psicologia , Suicídio/psicologia , Adulto , Estudos de Coortes , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Psicometria/estatística & dados numéricos , Reprodutibilidade dos Testes , Suicídio/estatística & dados numéricos , Tentativa de Suicídio/estatística & dados numéricos , Suécia
11.
Neuroscience ; 423: 12-17, 2019 12 15.
Artigo em Inglês | MEDLINE | ID: mdl-31704493

RESUMO

Sensitivity and reliability of animal behavioral assessment methods are critical for successful translation of in vitro findings to in vivo. Here we report a data transformation process in the elevated open platform task that generates a novel parameter, namely peak tolerance of fear (PTF) or its inversely correlated equivalent of anxiety quotient (AQ), to measure anxiogenic tendency in rodent. As compared to traditional parameters such as travel distance, time, or entries, PTF or AQ displays largely reduced data dispersion not only ingroup but also cross-study and cross-cohort, therefore representing a significant improvement of the methodology for rodent anxiety assessment.


Assuntos
Ansiedade/psicologia , Escala de Avaliação Comportamental/estatística & dados numéricos , Comportamento Animal , Análise de Dados , Aprendizagem em Labirinto , Animais , Feminino , Masculino , Camundongos , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
12.
Am J Intellect Dev Disabil ; 124(6): 483-496, 2019 11.
Artigo em Inglês | MEDLINE | ID: mdl-31756140

RESUMO

Communication Complexity Scale (CCS) scores for 269 minimally verbal participants were examined to determine if communicator behavior and task and communicator characteristics were related to scores in a manner consistent with theoretical and research evidence expectations. Each participant completed an interactive assessment with 6 joint attention tasks and 6 behavior regulation tasks. Caregivers completed the Vineland Adaptive Behavior Scales II. Results indicated (a) joint attention tasks yielded lower scores than behavior regulation tasks, (b) older participants had lower scores, (c) individuals with autism spectrum disorder scored more similarly than those without, (d) the difference between joint attention and behavior regulation scores was greater for the autism spectrum disorder group, and (e) adaptive behavior was significantly positively related to complexity scores.


Assuntos
Transtorno do Espectro Autista/diagnóstico , Escala de Avaliação Comportamental , Transtornos da Comunicação/diagnóstico , Relações Interpessoais , Autocontrole , Comportamento Social , Adolescente , Adulto , Idoso , Escala de Avaliação Comportamental/estatística & dados numéricos , Criança , Pré-Escolar , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem
13.
BMC Res Notes ; 12(1): 613, 2019 Sep 23.
Artigo em Inglês | MEDLINE | ID: mdl-31547866

RESUMO

OBJECTIVE: Although studies have shown inconsistent results in terms of prevalence of eating disorders, the Eating Attitudes Test (EAT-26) was used to screen students for abnormal eating behaviors. The results of the self-reported EAT-26 and body frame, as well as the efficacy of using self-administered questionnaires (SAQs) were examined to detect eating disorders in new college students. RESULTS: An anonymous questionnaire (EAT-26) was provided to 7738 new students; 4552 (58.8%) responders were included in the final analysis. Semi-structured interviews were conducted for 131 (1.7%) students. Among them, 6 students showed a high EAT-26 score, but were not diagnosed with an eating disorder based on the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I). Three students were diagnosed with an eating disorder using SCID-I, but their EAT-26 scores were below the threshold. From these results, in a non-clinical population, findings on EAT-26 do not agree with those on SCID-I in terms of the diagnosis of eating disorders, and this battery is not appropriate for detecting eating disorders.


Assuntos
Testes Anônimos/métodos , Escala de Avaliação Comportamental/estatística & dados numéricos , Comportamento Alimentar/psicologia , Transtornos da Alimentação e da Ingestão de Alimentos/diagnóstico , Adolescente , Adulto , Índice de Massa Corporal , Transtornos da Alimentação e da Ingestão de Alimentos/epidemiologia , Transtornos da Alimentação e da Ingestão de Alimentos/psicologia , Feminino , Humanos , Japão/epidemiologia , Masculino , Prevalência , Autorrelato , Estudantes , Inquéritos e Questionários
15.
Artigo em Inglês | MEDLINE | ID: mdl-31152861

RESUMO

Diabetes is a metabolic disease characterized by hyperglycemia because of insulin resistance and/or insufficient insulin release. The most common diabetic brain complications include cognitive decline and depression. The present study investigated whether the 4-4'-dichlorodiphenyl diselenide (p-ClPhSe)2 is effective against memory impairment induced by diabetes in mice and the role of hippocampal BDNF/TrkB signaling in this effect. Male adult Swiss mice received an injection of streptozotocin (STZ) (200 mg/kg, i.p.) to induce diabetes. The results revealed that STZ injection in mice resulted in resilience (glycemia <200 mg/dl) or diabetes (glycemia ≥200 mg/dl). The vehicle-control group received citrate buffer (5 ml/kg). The animals were subchronically treated with (p-ClPhSe)2 (1 or 5 mg/kg, i.g.) for 7 days. Mice performed a battery of well-validated behavior tests designated to evaluate memory, object recognition (ORT), object location (OLT), and Morris water maze (MWM). The hippocampal protein contents of the BDNF/TrkB pathway were determined in the samples of experimental groups. Fluoro Jade C (FJC) was used for staining degenerating neurons. The STZ administration resulted in memory impairment that was demonstrated in the mouse ORT, OLT, and MWM tests. The molecular findings indicate an increase in hippocampal protein levels of proBDNF and TrKB but a decrease in those of mBDNF and pCREB in diabetic mice. The number of FJC-positive cells was increased in the hippocampus of diabetic mice. (p-ClPhSe)2 at the dose of 5 mg/kg modulated the hippocampal BDNF/TrkB pathway, reduced FJC-positive cells and reversed memory impairment induced by STZ in mice. These findings demonstrate the effectiveness of (p-ClPhSe)2 against memory impairment caused by diabetes in mice. (p-ClPhSe)2 modulated the hippocampal BDNF/TrkB signaling pathway in diabetic mice.


Assuntos
Fator Neurotrófico Derivado do Encéfalo/metabolismo , Diabetes Mellitus Experimental/metabolismo , Hipocampo/metabolismo , Glicoproteínas de Membrana/metabolismo , Transtornos da Memória/prevenção & controle , Compostos Organosselênicos/farmacologia , Receptor trkB/metabolismo , Animais , Escala de Avaliação Comportamental/estatística & dados numéricos , Contagem de Células/estatística & dados numéricos , Proteína de Ligação ao Elemento de Resposta ao AMP Cíclico/metabolismo , Diabetes Mellitus Experimental/complicações , Relação Dose-Resposta a Droga , Fluoresceínas/metabolismo , Masculino , Transtornos da Memória/complicações , Camundongos , Fosforilação , Transdução de Sinais/efeitos dos fármacos , Estreptozocina
16.
Pediatr Nephrol ; 34(10): 1753-1764, 2019 10.
Artigo em Inglês | MEDLINE | ID: mdl-31222663

RESUMO

BACKGROUND: Psychosocial development of pediatric chronic kidney disease (CKD) patients is substantially affected due to growth retardation, frequent school absences, and difficulties engaging in normal peer relationship activities. While many studies focus on specific issues such as depression, anxiety, or neurocognitive function, few evaluate prevalence of various types of mental health and psychosocial adjustment problems among children with CKD. This study aimed to investigate these within the KoreaN cohort study for Outcomes in patients With Pediatric Chronic Kidney Disease (KNOW-Ped CKD). METHODS: One hundred sixty-six subjects who completed the Korean-Child Behavioral Checklist (K-CBCL) were included. The clinical group comprised subjects with scores indicating psychosocial adjustment or mental health problems using the T scores for the 14 subscales of the K-CBCL. We analyzed associations between mental health or adjustment problems in pediatric CKD and each variable. RESULTS: Mean age was 11.1 (± 3.9) years, number of males was 117 (70.5%), and 20.5% and 22.3% of children had significant mental health problems and psychosocial adjustment problems, respectively. Overall, 33.1% were assigned to the clinical group, and exhibited short stature and higher rates of preterm birth history compared to the non-clinical group. Subjects with adjustment problems had higher comorbidities such as CNS disease, developmental delay, cardiovascular disease, and multi-organ involvement. Logistic regression analysis revealed preterm birth and developmental delay correlated highly with clinical group. CONCLUSIONS: A significant proportion of children and adolescents with CKD experience mental health and adjustment problems. In particular, patients with developmental delay or preterm birth history require screening and targeted follow-up.


Assuntos
Transtornos de Adaptação/epidemiologia , Transtornos do Comportamento Infantil/epidemiologia , Deficiências do Desenvolvimento/epidemiologia , Saúde Mental/estatística & dados numéricos , Insuficiência Renal Crônica/psicologia , Transtornos de Adaptação/diagnóstico , Transtornos de Adaptação/psicologia , Adolescente , Escala de Avaliação Comportamental/estatística & dados numéricos , Criança , Transtornos do Comportamento Infantil/diagnóstico , Transtornos do Comportamento Infantil/psicologia , Estudos de Coortes , Comorbidade , Feminino , Humanos , Masculino , Prevalência , Estudos Prospectivos , Insuficiência Renal Crônica/complicações , Insuficiência Renal Crônica/epidemiologia , República da Coreia/epidemiologia
17.
Balkan Med J ; 36(5): 257-262, 2019 08 22.
Artigo em Inglês | MEDLINE | ID: mdl-31140236

RESUMO

Background: It is known that regular physical activity reduces anxiety. Low anxiety levels affect mood, emotions, and empathy. Oxytocin is a powerful hormone that regulates social interaction, sexual reproduction, maternal­infant bonding, milk release, empathy, and anxiety. Empathy is an important behavior in the living community; and also important for sportsmen during sportive competition and daily living life, because sportsmen are also role model of people. Aims: To investigate the effects of voluntary physical activity on oxytocin, anxiety, and empathy levels as well as the relationship between them. Study Design: Animal experiment. Methods: Male and female mice were made to exercise in running wheel cages for 6 weeks. Their empathy and anxiety levels were evaluated by using Helping Behavior test and elevated plus maze and open field test, respectively. And then the brain and blood oxytocin levels were measured. Results: Empathy-like behavior was improved in both genders of the exercise groups (door-opening time decreased in both genders of exercise groups, p for both=0.0001). As a response to exercise, both the brain and serum oxytocin levels increased in female mice (both of p=0.0001); however, in males, oxytocin levels increased in only the brain (p<0.05). Anxiety levels decreased in all the exercise groups (increased time spent in the middle area of open field test, both genders, p=0.002; increased time spent in the open arms of elevated plus maze test, females p=0.004, males p=0.0001). There was a strong negative correlation between serum oxytocin levels and door opening time of helping behavior equipment, and moderate negative correlation was found between the brain oxytocin levels and door-opening time of helping behavior equipment in females. However, there was no correlation between both the brain and serum oxytocin levels and empathy behavior in males. But there were very strong positive correlations between low anxiety indicators and both the brain and serum oxytocin levels in both the genders. Conclusion: Voluntary physical activity decreases anxiety and increases empathy-like behavior in mice; which is associated with increased oxytocin levels in female mice but not in male mice. Further research is required to investigate the mechanisms of exercise effect on anxiety and empathic brain pathways in males.


Assuntos
Ocitocina/fisiologia , Condicionamento Físico Animal/fisiologia , Animais , Ansiedade/classificação , Escala de Avaliação Comportamental/estatística & dados numéricos , Encéfalo/patologia , Encéfalo/fisiologia , Modelos Animais de Doenças , Empatia/classificação , Empatia/fisiologia , Feminino , Masculino , Camundongos , Estatísticas não Paramétricas
18.
J Psychiatr Res ; 115: 113-120, 2019 08.
Artigo em Inglês | MEDLINE | ID: mdl-31128501

RESUMO

A meta-analysis of the results of 45 factor analyses (n = 22,812) of the Positive and Negative Syndrome Scale (PANSS) was conducted. Meta-analyses of the PANSS was conducted using both a co-occurrence similarity matrix and reproduced correlations. Both methods produced similar results. Five factors (Positive Symptoms, Negative Symptoms, Disorganization, Affect and Resistance) emerged clearly across both analyses. The factors and the items defining them were Positive Symptoms (P1 Delusions, G9 Unusual thought content, P3 Hallucinatory behavior, P6 Suspiciousness and persecution, P5 Grandiosity), Negative Symptoms (N2 Emotional withdrawal, N1 Blunted affect, N4 Passive apathetic social withdrawal, N6 Lack of spontaneity, N3 Poor rapport, G7 Motor retardation, G16 Active social avoidance), Disorganization often termed Cognitive (P2 Conceptual disorganization, G11 Poor attention, N5 Difficulty in abstract thinking, G13 Disturbance of volition, N7 Stereotyped thinking, G5 Mannerisms/posturing, G15 Preoccupation, G10 Disorientation), Affect often termed Depression-Anxiety (G2 Anxiety, G6 Depression, G3 Guilt feelings, G4 Tension, G1 Somatic concern) and a small fifth factor that might be characterized as Resistance or Excitement/Activity (P7 Hostility, G14 Poor impulse control, P4 Excitement, G8 Uncooperativeness). Items G1, G4, G10, P5, G5, G15 may not be core items for the PANSS factors and G12 lack of judgment is not a core item. Results of the PANSS meta-analyses were relatively similar to those for meta-analysis of both the BPRS and BPRS-E all of which contain the original 18 BPRS items. The PANSS is distinguished by a much larger number of items to clearly define and measure Negative Symptoms as well as a sufficient number of items to much more clearly identify a Disorganization factor than the BPRS or BPRS-E.


Assuntos
Escala de Avaliação Comportamental/estatística & dados numéricos , Escalas de Graduação Psiquiátrica/estatística & dados numéricos , Transtornos Psicóticos/diagnóstico , Esquizofrenia/diagnóstico , Humanos
19.
Int J Offender Ther Comp Criminol ; 63(9): 1766-1775, 2019 07.
Artigo em Inglês | MEDLINE | ID: mdl-30947588

RESUMO

The Sexual Homicide Crime Scene Rating Scale for Sexual Sadism (SADSEX-SH) is a rating scale which dimensionally measures the degree of offender sexual sadism in suspected sexual homicide cases. Scoring is accomplished using crime scene and related investigative information. Preliminary norms for the SADSEX-SH prototype indicate that it correctly classified offenders with and without sexual sadism. This study further assessed SADSEX-SH sensitivity, specificity, and inter-rater reliability by comparing a larger sample of male sexual homicide offenders with (n = 20) and without (n = 20) sexual sadism. Two items generally undetectable at crime scenes were removed from the originally proposed 10-item scale, resulting in a final 8-item version. SADSEX-SH total scores for the two groups significantly differed (7.7 ± 3.5, range = 2-14 vs. 2.6 ± 2.0, range = 0-7, t = 5.58, p < .001). Inter-rater reliability was excellent (intraclass correlation coefficients [ICCs] = 0.6-1.0). Using a revised cutoff score of 6, sensitivity was 70.0% and specificity was 90%. This revised scale may prove useful for investigators, clinicians, and institutional professionals in helping to identify and address sexual sadism in sexual homicide offenders.


Assuntos
Escala de Avaliação Comportamental/estatística & dados numéricos , Homicídio/legislação & jurisprudência , Sadismo , Delitos Sexuais/legislação & jurisprudência , Adulto , Canadá , Homicídio/classificação , Humanos , Masculino , Psicometria/estatística & dados numéricos , Reprodutibilidade dos Testes , Delitos Sexuais/classificação , Estados Unidos
20.
Cad Saude Publica ; 35(3): e00179318, 2019 04 08.
Artigo em Português | MEDLINE | ID: mdl-30970100

RESUMO

The Tripartite Influence Scale (TIS) is used to assess the influence of social and family factors on individuals' body image. However, little evidence has been presented on the validity of the TIS construct. The study aimed to estimate the psychometric indicators in TIS and identify the degree of influence of the media, parents, and peers on body image in university students, considering different characteristics. University students of both sexes participated. The psychometric indicators in TIS were assessed for each sex using confirmatory factor analysis. Mean scores were calculated for each TIS factor. Prevalence rates for degree of influence were presented. A multivariate regression model was built to verify the relationship between target characteristics and TIS factor scores. The sample included 791 university students (63.2% women) 18 to 40 years of age. TIS did not initially display a good fit to the samples and was therefore refined. After refinement, the scale showed adequate validity and reliability for women and men. Significant differences were observed in the mean scores between women and men, and in the prevalence rates the majority of the students were in the low category. Work, consumption of food supplements for body changes, age, body mass index, self-rated diet, and level of physical activity were significantly related to TIS factors. Women were generally more influenced than men by the media and peers. Characteristics identified as related to TIS can be relevant for inclusion in clinical and research protocols.


A Escala de Influência dos Três Fatores (TIS) é utilizada para avaliar a influência de aspectos sociais e familiares na aparência corporal dos indivíduos. Contudo, poucos indícios de validade de construto da TIS são apresentados. O objetivo do estudo foi estimar os indicadores psicométricos da TIS e identificar o grau de influência da mídia, pais e amigos na aparência corporal de universitários considerando diferentes características. Universitários de ambos os sexos participaram. Os indicadores psicométricos da TIS foram avaliados para cada sexo utilizando análise fatorial confirmatória. Os escores médios de cada fator da TIS foram calculados. As prevalências do grau de influência foram apresentadas. Um modelo de regressão múltiplo multivariado foi construído para verificar a relação de características de interesse com os escores dos fatores da TIS. Participaram 791 universitários (63,2% mulheres) de 18 a 40 anos. A TIS não apresentou bom ajustamento às amostras e foi refinada. Após refinamento, observou-se adequada validade e confiabilidade para mulheres e homens. Verificaram-se diferenças significativas entre os escores médios de mulheres e homens, e, nas prevalências, a maioria dos estudantes esteve na categoria baixa. A atividade laboral, o consumo de suplementos alimentares para alterar o corpo, a idade, o índice de massa corporal, a autoavaliação da alimentação e o nível de atividade física se relacionaram significativamente com os fatores da TIS. Em geral, as mulheres foram mais influenciadas pela mídia e pelos amigos do que os homens. As características amostrais identificadas como relacionadas aos fatores da TIS podem ser relevantes para inclusão em protocolos clínicos e de pesquisa.


La Escala de Influencia de los Tres Factores (TIS) se utiliza para evaluar la influencia de aspectos sociales y familiares en la apariencia corporal de los individuos. A pesar de ello, en el constructo de la TIS se presentan pocos indicios de validez. El objetivo de este estudio fue estimar los indicadores psicométricos de la TIS e identificar el grado de influencia de los medios de comunicación, padres y amigos, en la apariencia corporal de universitarios, considerando diferentes características. Participaron universitarios de ambos sexos. Los indicadores psicométricos de la TIS se evaluaron para cada sexo, utilizando un análisis factorial confirmatorio. Se calcularon las puntuaciones medias de cada factor de la TIS. Se presentaron las prevalencias del grado de influencia. Se construyó un modelo de regresión múltiple multivariado para verificar la relación de características de interés con puntuaciones de los factores de la TIS. Participaron 791 universitarios (63,2% mujeres) de 18 a 40 años. La TIS no presentó un buen ajuste a las muestras y fue depurada. Tras la depuración se observó una validez adecuada y confiabilidad para mujeres y hombres. Se verificaron diferencias significativas entre las puntuaciones medias de mujeres y hombres, asimismo, en las prevalencias la mayoría de los estudiantes estuvo en la categoría baja. La actividad laboral, consumo de suplementos alimenticios para alterar el cuerpo, edad, índice de masa corporal, autoevaluación de la alimentación y nivel de actividad física se relacionaron significativamente con los factores de la TIS. En general, las mujeres estuvieron más influenciadas por los medios y por los amigos que los hombres. Las características de las muestras identificadas y relacionadas con los factores de la TIS pueden ser relevantes para su inclusión en protocolos clínicos y de investigación.


Assuntos
Escala de Avaliação Comportamental/estatística & dados numéricos , Imagem Corporal/psicologia , Família/psicologia , Estudantes/psicologia , Inquéritos e Questionários/estatística & dados numéricos , Adolescente , Adulto , Índice de Massa Corporal , Brasil , Estudos Transversais , Análise Fatorial , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Psicometria , Reprodutibilidade dos Testes , Fatores Sexuais , Fatores Socioeconômicos , Universidades , Adulto Jovem
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